Thursday, May 14, 2009

Need for certification of Medical Representatives

EDITORIAL for NetRUM ©
Need for independent national certification for medical representatives
Dr Vijay Thawani, Group Owner, NetRUM
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Market forces always dictate the change and stimulate development. For the existing staff in specialized services, the impetus brings in new era of improvements, continuing education, and training. Every change is initially resisted because we fear the uncertainty of the unknown. Sound justification with good understandable reasoning catalyses acceptance of the change.
Medical representatives (MRs) are important stake holders in the delivery of health care to society. In our part of the world, unfortunately they have not received due position of respect and are relegated to be mere “agents” of the pharma companies, trying to “push” the products.
The MRs in the past were popularly known as “human parrots” who were taught limited knowledge about the company’s products, made to memorize, then recall it for medical doctors to influence their prescription. The medical directors of the pharma companies turned these detailers into polite glib talkers, likable personalities who were easy to talk to, who always “agreed to agree”, to appease the prescribers. They were considered as “couriers” of medicine samples and company gifts. The era of modern management converted them into human tool to effectively impress the prescribers.
Critics have often objected to the impact of MRs on medicine prescription and making buffoons out of intelligent doctors. The MRs can sway the opinion of doctors in favor of their products in minutes, a claim which is so true but yet denied by the medical professionals.

The advantages of certification
Pharma industry is facing tough times, fierce competition, bad name, and hence there is need to enhance its standards, establish better image and improve credibility. Hence the need for setting up a national standard for certifying medical and pharmaceutical sales representatives, who can perform the good work of ethical and rational promotion of medicines.
It is felt that certification of MRs will usher in requisite basic knowledge base, improve work ethics and impart good name to the industry they work for. By voluntarily elevating the level of knowledge, MRs will demonstrate greater commitment and accountability. Ultimately they will become better professionals, who will perform better in improving the health of populations through the medics with whom they interact.
The standardization brought in through the certification will ensure more focused, better versed and trained MRs, capable to talk about the technical things and answering the questions of medical fraternity. Medical doctors will certainly like to interact more with a MR who is certified. A tremendous potential remains to be harnessed in bringing in the change, the way MRs interact with medical doctors. With the certification the quality of the information flow will improve which will be more consistent. It will also make the MRs more marketable for their careers.

What all will come in with certification
The certification program will succeed if it is managed by a single, national autonomous council with absolute powers and total independence. This institution should not use tax payers’ money and also not receive funds from the industry. It should be self sufficient to earn through registrations, training, CMEs, examinations and certification. Once the exams for certifying MRs get going, it will be self-sustaining.
This council will conduct activities and programmes to educate and train the MRs to bring them up to the set uniform standard, so that they can be groomed. Need based changes can be introduced in the curriculum to keep the MRs updated with current trends. Such trained manpower with acquired skill set can then be examined for the certification meant for representatives of medical, pharmaceutical and biotech companies. The certification process must focus on measuring competency in science, medicine, pharmacology, disease state management, evidence-based medicine, ethics and compliance, rational promotion of medicines.
In addition to establishing the initial certification examination, the council must establish procedures for periodic renewal of the certification and requirements for CME. It should be alike international certification programs for other health care industry workers. The goal is to have a voluntary certification and examination system in place.
The in-service employees enrolled for such educational courses can be sponsored by their employers because finally the pharmaceutical and other medical companies, who pay for their up gradation and consequent certification, will benefit from their acquired knowledge and skills.

Recommendation
Transparency of working, openness to public scrutiny and changes in the industry are compelling the change for how MRs perform their jobs. The national certification will ensure in delivering better professionals to whom the medical profession can look up to for scientific, evidence based, and high quality helpful information. As the momentum for changing the MRs is growing, the health care has to speedily introduce the reform to stand up to the call.
It is fact that in India the majority of doctors depend for medicine information and new medicines on MRs. The certification process will assure doctors and patients that good, useful information is being shared by competent stake holders.

Thursday, December 28, 2006

my CV

Dr. Vijay Thawani
E-Mail: vijaythawani@rediffmail.com
Blog: http://vijaythawani.blogspot.com
Netgroup: http://groups.yahoo.com/group/netrum

Summary: Working as Associate Professor in Pharmacology at Government Medical College, Nagpur, India, with experience of 27 years in medical teaching and 22 years in research and administration. Good communicator, prolific writer, with 100 research publications. Widely traveled, have been invited for presentations in US, Thailand and many places in India. I have two patent applications pending with US Patents and Trademark Office. I was co-investigator for WHO project on Hospital Waste Management and WHO-HAI project on medicine pricing. Recipient of appreciation letter from WHO SEARO, I am a trained faculty for rational use of medicines and have been trainer in international courses. I have been invited by WHO, SEARO as resource person for training course on rational use of medicines. I have coordinated courses conducted in collaboration with WHO and ICMR. Participated in Technical Briefing Seminar at WHO headquarters, Geneva, Switzerland on WHO funding. Owner and moderator of yahoo group – Netrum.


Academic Qualifications: MBBS, MD (Pharmacology), MA (Sociology), MA-I (Public Administration), Bachelor of Journalism, Postgraduate Diploma in Pubic Relations (Gold Medal), Postgraduate Diploma in Gandhian Thought (Topper), Certificate in Social Welfare Administration.

Computer Literacy: Certificate in Office Automation

Present Employment: Associate Professor in Pharmacology, Government Medical College, Nagpur.

Other responsibilities at the college:
Executive Committee member of Alumni Association
Supervisor in-charge of outdoor dispensaries.
Was in-charge of Medical Stores, Super Specialty Hospital
Was teacher-in-charge of Students' Council
Was Editor of English section of the college magazine
Was Teacher-in-charge, Postgraduate Teaching, Department of Pharmacology
Was Students’ Councilor

Teaching Experience: 27 years

Recipient of appreciation letter:
From the Regional Director, World Health Organization, Regional Office for South East Asia for safeguarding the integrity of WHO reputation in medicines.

Research:
· Published 100 papers in indexed, national, international medical journals.
· 20 papers pending publication with various journals.
· Research project funded under “Star Research Project” scheme of The Medical Research Council of Maharashtra, Directorate of Medical Education & Research, Government of Maharashtra.
· Associated with 4 ongoing research projects.
· Presented research paper at Second International Conference on Improving Use of Medicines (ICIUM -2004) at Thailand in March 2004 on WHO sponsorship.
· Was co-investigator for WHO project (No. INHEHH 001) on Baseline study for hospital waste management.
· Was co-investigator of WHO and Health Action International (HAI) funded project on Medicine Pricing.
· Guided the study, which won Prof U. K. Sheth award for best paper in Clinical Pharmacology at 35th All India Conference of Indian Pharmacological Society held at DRDE, Gwalior in 2002.
· First recipient of 10% reprint revenue (Rs.12,000) share from Indian Journal of Pharmacology out of Rs 1,20,000 earned by journal on sale of reprints of a published paper.
· Was guide / trial monitor of the research projects which were awarded Indian Council of Medical Research (ICMR) Short Term Research Studentship in 2003, 2004, 2005 and 2006.
· Was guide of the research project, which received Rs.1.35 lakh grant under Sir Madhavrao Chitnavis Clinical Research Fellowship for 2003 -04.
· Applied for two patents with US Patent & Trademark Office.
· Hundreds of citations on search engines as “V+Thawani” and “Vijay+Thawani”.
· Recognized PG Guide for MD (Pharmacology) and supervisor for PhD of Nagpur University.
· Was clinical pharmacologist member of Ethics Committee of Govt Medical College, Nagpur.

Medical Journalism:
· Editorial board member and peer reviewer - Indian Journal of Pharmacology.
· Member of the Scientific Advisory Board and peer reviewer - The Milestone, Journal of Directorate of Medical Education and Research, Govt. of Maharashtra.
· Reviewer - Journal of Postgraduate Medicine.
· Reviewer - Journal of Ethnopharmacology.
· Book Reviewer - The Antiseptic.
· Published invited editorial in Indian Journal of Pharmacology.
· Published many invited articles in national and local newspapers and magazines.
· Edited book on Human Genetics.
· Edited In-house journals/magazines of Government Medical College Nagpur and V.N. Government Medical College, Yavatmal.
Invited as Faculty / Guest Speaker at:
· 34th Annual Conference of Indian Pharmacological Society, Nagpur, 2001. Topic: Medicine promotion.
· 18th All India Steel Medical Officers’ Conference, JLN Hospital & Research Centre, Bhilai Steel Plant, Bhilai (7-9 Feb 1997).
· All India Conference of Industrial Psychiatrists, Rourkela.
· Tata Main Hospital, Tata Steel, Jamshedpur (28 Sept 1997).
· Tata Hospital, Jamadoba
· Indian Pharmacological Society, Vidarbha Branch
· Indian Medical Association (IMA) Zonal Conference of Chattisgarh Region, Durg, (17 Aug1997).
· IMA Workshop on self-assessment of medical professionals, Raipur (11 Jan1998).
· IMA Kanhan-Kamptee
· Vidarbha ENT Conference, Yavatmal
· New Millennium World Congress on Alternative Medicine & Therapies, Mumbai (6-8 Apr 2000)
· National Aids Control Organization (NACO) workshop on AIDS
· Nagpur University, Govt. Dental College Nagpur, Ayurvedic College Yavatmal, MSS Institute of Social Work, Manganese Ore India Ltd, Lions Club MIDC Nagpur, and many other places.
· USA for research presentations in two international conferences on sponsorship (in Sept - Oct 2003).
· 5th Indian Council of Medical Research (ICMR) Training Course in Clinical Pharmacology in Traditional Medicine at Nair Hospital, Mumbai (6-15 Sept 2004).
· Short Term Training Programme on Basic Laboratory Techniques in Molecular Biology sponsored by Department of Biotechnology, Ministry of Science & Technology, Govt. of India at Sindhu Mahahavidyalaya, Nagpur (9 July 2005). Topic: Research in herbal medicines.
· Medical Council of India (MCI) sponsored symposium on Rational use of antibiotics, Department of Microbiology, Government Medical College, Nagpur (1 Oct 2005).
· Resource person for “International Course on Rational Use of Medicines in Community” at Indian Institute of Health Management Research, Jaipur (15-24 Jan 2006).
· Resource person for “Training course on promoting rational medicine use in the community” conducted in collaboration with WHO's Essential Drugs and Other Medicines, SEARO, at Govt. Medical College, Nagpur (1 – 8 Mar 2006).
· “Putting patients first” seminar organised by Health Education Library for People (HELP), Mumbai. Topic: Educating patients about their medicines. (7-8 Apr 2006)
· Silvercon – 2006 on “Making medicine consumer friendly” organised by IPS Gujarat chapter at B. J. Medical College, Ahmedabad. Topic: Information therapy and patient empowerment. (8 Oct 2006)
· All India Council for Technical Education (AICTE) sponsored Staff Development Programme “Recent trends in quality assurance of pharmaceuticals” at Sharad Pawar College of Pharmacy, Nagpur. Topic: Rational use of medicines. (13 Oct 2006)
· Medical Staff Research Society, Govt. Medical College Nagpur. 24 Nov 2006. Topic: Writing a good manuscript.
· International training course on promoting rational drug use in the community at IIHMR, Jaipur (10 -21 Dec 2006).

Organized many conferences/CME/Workshops/courses, of which notable are:
¨ Was Organizing Secretary of 2nd Conference of South Asia-Pacific Society of Human Genetics and 25th Annual Conference of Human Genetics at Nagpur (9-10 Jan 2000).
¨ Was Coordinating Secretary, 34th Annual Conference of Indian Pharmacological Society, Nagpur (10-12 Jan 2002).
¨ Was course coordinator for “Training course on promoting rational medicine use in the community” conducted in collaboration with WHO's Essential Drugs and Other Medicines, SEARO (01 – 08 March 2006).
¨ Was course coordinator for WHO sponsored “Training of trainers’ workshop on integrating clinical pharmacology, concept of essential medicines and rational medicine use into the UG curriculum “(17 Aug 2006).
¨ Was course coordinator for ICMR sponsored “Workshop on biomedical communication in cyberage” (18-20 August 2006).

Courses / Workshops attended:
Ø National workshop on Clinical Pharmacology at PGI Chandigarh (13-18 Feb 1995).
Ø Training programme on Hospital clinical waste: Hazards, management and infection control at Indian Society of Health Administrators at Bangalore (24-26 June 1999).
Ø Maharashtra University of Health Sciences Convention on Interpathy Research Policies & Priority Areas in Research at Nashik (18-20 Jan 2000)
Ø ICMR Workshop on Biomedical Communication in Cyberage at JIPMER, Pondicherry (23-25 Aug 2001)
Ø Maharashtra University of Health Sciences Regional Workshop on Development of Integrated Teaching at Nagpur (29-30 Jan 2002)
Ø ICMR Workshop on Clinical Pharmacology of Traditional Medicine at Nair Hospital, Mumbai (13-23 March 2002)
Ø Regional Workshop on Good Clinical Practices organized by Pfizer & Pharmacology Research Society, IGMC Nagpur (9-10 Dec 2002)
Ø Pre-survey workshop on Medicine Prices conducted by WHO and HAI at Hyderabad (14-16 April 2004).
Ø Training Programme on Intellectual Property Rights at Intellectual Property Training Institute, Government of India, Nagpur (12-14 May 2004)
Ø Promoting Rational Drug Use in the Community by WHO, Indian Institute of Health Management Research, Jaipur (23-30 Jan 2005)
Ø Post-survey workshop on Medicine Prices conducted by WHO and HAI at Goa (21-23 June 2005).
Ø Regional workshop on Biomedical and municipal solid waste at Tata Institute of Social Sciences (TISS) by Toxics Link and TISS at Mumbai (23-24 May 2006).
Ø Biomedical Information Retrieval at National Informatics Centre, New Delhi (17-21 July 2006).
Ø WHO/ UNICEF Technical Briefing Seminar at WHO Headquarters, Geneva, Switzerland (18-22 Sept 2006).


Association with medical organizations:
v Life member, Indian Pharmacological Society
v Life member, Association of Physiologists and Pharmacologists of India
v Patron, Thalessemia Society of India, Nagpur
v Director, Indian Academy for Rational Use of Drugs
v Chief Editor, Indian Pharmacological Society, Vidarbha Chapter.
v Patron, Sindhi Medicos’ Association, Nagpur
v Life Member, Rashtra Sant Tukdoji Maharaj Cancer Hospital, Nagpur.
v Life member and Executive Committee Member, Govt. Medical College Alumni Association, Nagpur.

National Cadet Corps (NCC)
As an Officer:
· Was Associate NCC Officer for 15 years
· Last rank: MAJOR (NCC)
· Last designation: Second-in-command of 2 Maharashtra Medical Company NCC.
· Recipient of commendation certificates from all Group Commanders under whom worked.
· Recipient of commendation medal from Director General NCC.
· Qualified two Medical Officers Junior Command Courses of Ministry of Defence, Govt. of India from Army Medical Corps School and Training Centre, Lucknow. Stood 5th in order of merit in one of them.
· Qualified Parasailing Instructor Cadre.
· Provided medical cover to DG NCC All India Trekking Expedition “Shivaji Trail”.

As a Cadet:
· Was Senior Under Officer
· Qualified Basic Paratroopers Course
· Qualified Advanced Leadership Course in rock climbing
· Was Best Cadet of the Unit – 2 Maharashtra Medical Company NCC
· Was Best Cadet from Senior Division (Boys) of NCC Group Head Quarters Nagpur
· Passed B and C Certificate examinations
· Was Vice Chancellor’s nominee from NCC on Nagpur University Students’ Council.

As a student in Govt. Medical College:
Was Class representative
Was College Representative in Nagpur University
Was Captain of college Football and Hockey teams
Played in All India Inter Medical Hockey Tournaments
Was General Secretary of Sports & Games Association
Was Founder member and Treasurer, Voluntary Blood Donors’ Organization
Was Founder member and Secretary, Interns’ Association

Adventure Sports:
· Founder President, Nagpur Trekkers’ Association.
· Life member, Nagpur Mountaineers.
· Participated in five National Himalayan Trekking Programmes organized by Youth Hostels Association of India. Was Group Leader of two.

Civil Defence:
Qualified Basic Civil Defence Course of Govt. of Maharashtra with Distinction.

Saturday, November 05, 2005

Our Research in Herbal Medicine

India has tremendous herbal wealth and traditional knowledge associated with it. Known by various names like home remedies, tribal medicine, traditional medicine and Ayurveda, we have many plant based products meant for health needs. Calling this as alternate medicine is incorrect, unjustified and insulting since the connotation of ‘alternative’ is that it is secondary to something else. Rightfully this must get the first place because it has existed and was practiced prior to the entry of other pathies on medical scene. It was the under use and disuse of our own repertoire which enabled the other pathies to grow aggressively over it.

For any country the indigenous medicine has national pride because it has developed locally over the centuries and is time tested. It should be practiced with honour, refined with interest and spread with intention. China, Japan, Korea and many other countries proudly practice their own medicine. Even the Tibetans in India practice Tibetan medicine. Geographically Unan is not existing but India has medical colleges and hospitals, which teach and practice Unani medicine.

The rise of modern medicine has occurred in last century. Prior to it the human civilization has not only survived but also prospered and blossomed to present state. The human development did occur without industrial products and was solely dependant on nature. Our ancestors did not require the chemicals to keep them disease free.

While some allopathic medicines do have remarkable efficacy and speedy action like analgesics, antipyretics and antimicrobials, most of the medicines only provide symptomatic relief and do not cure the diseases like hypertension, diabetes and ischemic heart diseases. It is the current generation, which seems to have forgotten the use of indigenous herbal medicine and is over dependant on imported pathies.

There are many modern medicines, which are derived from the herbal sources. It is most unfortunate that we have to be informed about the utility of haldi through advertisements of turmeric creams, face packs are sold more than multani mitti, irrational cough mixtures are consumed but not home made anticough kadha, liquorice containing lozenges are sucked but not the jyestha madh, menthol is preferred over pudina, fancy garlic pearls are preferred over raw lahsun without realizing that only names are firangi but the contents are desi!

Getting started in herbals
Our trainers in traditional medicine told us about their research on Tinospora Cordifolia. We decided to get started with it. We went through the published papers on this, understood that it was an immunostimulant and then looked at extrapolating this. We prepared a list of immune compromised conditions and then searched bibliography databases to narrow down on the diseases where efficacy of Tinospora was not tested. Then we chose the condition where the trial will be feasible in our set up. While the published papers have been quoted, details of others which are yet to be published have been given in parenthesis.

This led to the conceptualisation of our first project to find the efficacy of Tinospora Cordifolia extract (TCE) in Allergic rhinitis patients 1, the critical review of which is also positive 2. Having tested the success with first project, we extended the TCE research in thermal burns (Gunjan Gangrade, ICMR UG Research Studentship Project 2003), then in HIV positive patients (Dr Sonali Pimpalkhute, Sir Madhavrao Chitnavis Clinical Research Fellowship for 2003-04, with funding), then in Hensen’s disease (Dr Kavita Jaiswal).

We looked at the diseases which were commonly prevalent in India, where modern medicine did not offer complete cure, there was bibliographical evidence for use of indigenous herbs, the herb was still available, no paper was published in any scientific journal on the study we planned and the study was feasible within our available resources. During our readings we realised that the Sanskrit and vernacular names of Indian herbs had great significance. That is how we came to Gajabhaksha.

Boswellia Serrata
It made interesting reading to know that Elephant torso to leg ratio was more than humans, they were on their legs for longer time than us, survived longer and yet did not suffer from arthritis of knee. They consumed the bark of the tree, which was therefore called Gajabhaksha 3. This led to evaluating its efficacy in osteoarthritis of knee (Dr Nitin Kimmatkar, international publication 4, critical review in another international journal 5 and more than 100 citations on various search engines), then we did our first kinetic study (Dr Sunita Sharma, Dr U. K. Sheth award for best presentation in Clinical Pharmacology in national conference, international publication 6) and have just completed its comparative trial with an established non-steroidal anti inflammatory drug (Dr Smita Sontakke).

Cissus Quadrangularis
With vernacular names Hadjod, Asthishrankhala and alike, it attracted our attention since no fracture healing medicine is known in modern medicine. We found that bonesetters used the poultice of this in treatment of fractures. This led to evaluation of its efficacy in fractures of long bones, where we found it to be effective 7. Then we hypothesised that it may be effective in low bone mineral density 8,9 where we did find it effective (Dr Sarang Dhatrak, MD dissertation) and later extended the research to peri-menopausal women (Dr Vikrant Deshmukh). Our first in-vitro research project showed that it also had antibacterial properties 10(Dr Sushil Makhija).

Bacopa Monnieri
The Indian name Brahmi is well known and CDRI Lucknow has done extensive research on it. Many companies manufacture products for memory improvement containing Brahmi. We thought of evaluating its efficacy on medical students (Navneet Kumar, ICMR UG Research Studentship Project 2004). Having found it effective, we have extrapolated it to senile dementia (Dr Anand Saoji) and have plans to test it in Alzheimer’s patients.

Punica Granatum
We read that Pomegranate is one of the best anti-oxidants, which led to planning of its biochemical and kinetic study (Bharati Manglani, PhD thesis). We are also screening its efficacy in Coronary Artery Disease patients (Navneet Kumar, ICMR UG Research Studentship Project 2005) and also looking at its in-vitro action.

Asparagus Recemosus
A practicing Gynaecologist gave a herbal combination product to my wife for her menopausal syndrome. On enquiry she confirmed its efficacy and also informed that her patients were satisfied with the formulation in alleviating menopause associated problems. While working on one such product we realised that its major constituent was Shatavari 11. Hence we planned the study to evaluate the efficacy of extract of Asparagus Recemosus in menopausal syndrome (Dr Leela Abhichandani, PhD thesis).

Other Projects on Herbals
Our research group members have also worked on many other herbal extracts like Ginger 12 (Dr Smita Borkar, MD dissertation), Guggul, Karela and Neem 13 (Dr Atul Raut, MD dissertation), Banana leaf (Dr Varsha Sagdeo) and an antidiabetic herbal combination 14.

While names of only principal investigators have been mentioned, there are many co-investigators in each project and our “Team Indigenous” is able to forge ahead because of their continued interest, dedication and enthusiasm. More than 40 researchers from various specialities have been associated with various projects. Herbal research is teamwork and needs great inputs. Salutations to those who have shown the power to sustain and have been continuing in herbal research. The coming years will see dozens of papers on herbal research from our group in various medical journals.

References

1. Badar VA, Thawani VR, Wakode PT, Shrivastava MP, Gharpure KL, Hingorani LL, Khiyani RM. Efficacy of Tinospora cordifolia in allergic rhinitis. Journal of Ethnopharmacology, Jan 2005, 96 (3): 445-449.

2. Bader VA, Thawani VR, Wakode PT, Shrivastava MP, Gharpure KJ, Hingorani LL, Khiyani RM. Jury still out on the usefulness of a traditional herbal medicine for allergic rhinitis. Focus on Alternative and Complementary Therapies. Appearing in Sept 2005.

3. Sontakke SD, Thawani VR, Gharpure KJ, Patel SB. Herbals in osteoarthritis. Milestone, Jan 2004, 3 (1): 25-28.

4. Kimmatkar N, Thawani VR, Hingorani LL, Khiyani RM. Efficacy and tolerability of Boswellia serrata extract in treatment of osteoarthritis of knee - a randomized double blind placebo controlled trial. Phytomedicine, Feb 2003, 10: 3-7.

5. Thawani VR. Positive study of Boswellia serrata for knee osteoarthritis suffers from methodological flaws. Focus on Alternative and Complementary Therapies, Sept 2003; 8 (3): 316-317.

6. Sharma S, Thawani VR, Hingorani LL, Shrivastava MP, Bhate V, Khiyani RM. Pharmacokinetic study of 11-keto b Boswellic acid. Phytomedicine, March 2004,11: 255-260.

7. Thawani VR, Kimmatkar N, Hingorani LL, Khiyani RM. Effect of herbal combination containing cissus quadrangularis in fracture healing. The Antiseptic, Sep 2002, 99(9): 345-347.

8. Gharpure KJ, Thawani VR, Dhatrak SD, Patel SB. Cissus Quadrangularis-a promising herb in fracture healing and osteoporosis. The Antiseptic, June 2004, 101 (6): 225-226.

9. Thawani VR, Dhatrak S, Gharpure KJ, Thakre S, Patel SB. Traditional medicine in osteoporosis. Orthopedics Today, Apr-Jun 2004, 6 (2): 117-120.

10. Makhija SF, Chande C, Powar R, Thawani VR. Antimicrobial activity of cissus quadrangularis linn in-vitro. Appearing in The Antiseptic. Aug 2005.